FAQS | Value sets

How can I ask for permission or advice to conduct an EQ-5D valuation study?

Please contact our scientific director.

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Which valuation protocol was used for the EQ-5D-5L?

A standardized valuation study protocol (called EQ-VT) was developed by the EuroQol Group to create standard value sets for the EQ-5D-5L. This protocol is based on the use of the composite time trade-off (cTTO) valuation technique, supplemented by a discrete choice experiment (DCE). We recommend EQ-5D-5L users to use the standard value sets, as these…

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Which techniques can be used to conduct a valuation study?

Several valuation techniques have been used to generate these value sets: time trade-off (TTO), visual analogue scale (VAS), and more recently, discrete choice experiments (DCE).

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Which value set(s) should I apply in case of an international study?

If you need to obtain health state utility values for the EQ-5D-5L, the recommendation is to use the United States EQ-5D-5L value set from Pickard et al. (2019) as the United Kingdom valuation study is currently ongoing. If you need to obtain health state utility values for the EQ-5D-3L, it is recommended to use the…

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Why is it not appropriate to use the adult EQ-5D-3L to calculate the EQ-5D-Y index value?

Until recently, no value sets were available for EQ-5D-Y because research showed that the approach used to value EQ-5D-3L health states for use in adult populations was not appropriate when valuing EQ-5D-Y health states for use in economic evaluations of healthcare interventions for paediatric-age populations. Evidence has showed that health states are valued differently when…

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What is the difference between the VAS, TTO and DCE techniques? Can they all be used to generate a quality adjusted life year (QALY) score?

The time trade-off (TTO), visual analogue scale (VAS) and discrete choice experiment (DCE) value sets differ in the technique used to elicit the values for the models. In the TTO task, respondents are asked to imagine they live in a certain suboptimal health state for 10 years and then to specify the amount of time…

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If there is no value set for my country, I am supposed to use an existing value set for a similar population. How do I assess whether a population is sufficiently similar?

Please see this webpage on choosing a value set. Many factors determine if another country’s value set can be used, such as geography, religion, language, level of development of the country, healthcare system etc. In addition, local HTA guidelines may come into play. Therefore, it is advised to contact local regulatory authorities about their requirements.…

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How should EQ-5D data (value sets) from multinational clinical trials be used?

Data on EQ-5D health states gathered in the context of a multinational trial may be converted into a single summary index using one of the available EQ-5D-3L value sets. There are different options available to do this using appropriate value sets, however, the choice depends on the context in which researchers or decision makers will…

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Why are general population values sets used?

To undertake a utility analysis, you will need to use a value set. Generally speaking, utility analysis requires a value set based on preferences from a general population. The rationale behind this is that the values are supposed to reflect the preferences of local taxpayers and potential receivers of healthcare. The EQ-5D value sets are…

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How are value sets obtained?

EQ-5D value sets are created by conducting a valuation study. In an EQ-5D valuation study, respondents (often members of the general public) are asked to indicate how good or bad some of the EQ-5D health states are. The answers are then combined into a statistical model, with which the value set is created. See here…

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