Translation certificates for Paper Self-Complete versions are applicable for all corresponding modes of administration and can be provided upon request. Translation certificates only confirm and reflect the most extensive translation procedure and will not be revised whenever minor or major modifications are being made which in itself does not change the procedure.

Until recently, no value sets were available for EQ-5D-Y because research showed that the approach used to value EQ-5D-3L health states for use in adult populations was not appropriate when valuing EQ-5D-Y health states for use in economic evaluations of healthcare interventions for paediatric-age populations. Evidence has showed that health states are valued differently when used to describe an adult or a child, that valuation techniques suitable for valuing ‘adult’ health states may be unsuitable for valuing ‘youth’ health states, and that health state values are affected by the wording used in the instrument (EQ-5D-Y vs EQ-5D-3L). Consequently, EQ-5D-3L value sets should not be used to assign values to EQ-5D-Y health states.

To undertake a utility analysis, you will need to use a value set. Generally speaking, utility analysis requires a value set based on preferences from a general population. The rationale behind this is that the values are supposed to reflect the preferences of local taxpayers and potential receivers of healthcare. The EQ-5D value sets are therefore based on the values of the general population.

EQ-5D is used by scientists across the world in different settings and for many different diseases. It is used by academia (e.g. universities, research institutes), governments (national, regional, municipal), industry (e.g. pharmaceuticals, medical devices) and by hospitals and clinics (e.g. hospitals, GP practices). At an international level, the pharmaceutical industry and scientific groups are the foremost users of the instrument. EQ-5D is frequently used in (multinational) clinical trials by pharmaceutical companies.

If you need to obtain health state utility values for the EQ-5D-5L, the recommendation is to use the United States EQ-5D-5L value set from Pickard et al. (2019) as the United Kingdom valuation study is currently ongoing. If you need to obtain health state utility values for the EQ-5D-3L, it is recommended to use the United Kingdom value set from Dolan et al. (2002).