Should I switch from EQ-5D-Y-3L to EQ-5D-Y-5L?

Deciding whether to use the EQ-5D-Y-3L or the EQ-5D-Y-5L in any given context depends on many factors, including a study’s characteristics and aims, and the study population. The EQ-5D-Y-3L may be more appropriate in some instances, for example in younger populations, those with low literacy, or where interviewer-administration is required, as it is likely somewhat easier to understand, and may be easier to follow in an interview setting. If increased sensitivity and reduced ceiling effects are a relevant consideration, then EQ-5D-Y-5L may be more appropriate. Likewise, in studies which follow respondents from childhood/adolescence to adulthood, or which mix adult and paediatric populations, it is probably preferable to use the EQ-5D-Y-5L in conjunction with the EQ-5D-5L (for adults) as it is likely to be easier to compare and, potentially, aggregate data between those two versions than between the EQ-5D-Y-3L and EQ-5D-3L, due to the greater differences in content between the latter two versions. In studies in which preference-weighted values (utilities) are needed, e.g. in economic analysis, it should be noted that value sets are only currently available for EQ-5D-Y-3L, though EQ-5D-Y-5L value sets will become available in the future.

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