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Comparing EQ-5D-3L and EQ-5D-5L value sets

Even though less people report full health on the EQ-5D-5L, as compared to the EQ-5D-3L, the average severity of reported problems is also less (i.e. slight problems instead of moderate problems). Implications for how scores obtained from the 3L and 5L compare depend on the values attached to certain health state and this varies across country/region. In some countries/regions, 3L and 5L results will be similar, while in other countries/regions 3L and 5L values may be different. While methodological differences in the way the 3L and 5L value sets have been created impair comparability, it is clear that the most extreme level of the mobility level is important to consider in relation to differences in the value ranges between the 3L and 5L: “Confined to bed” (EQ-5D-3L) is associated with larger disutility than “unable to walk” (EQ-5D-5L) (Law et al 2018).

Study TitleFirst AuthorJournalYearType
Head-to-Head Comparison of EQ-5D-3L and EQ-5D-5L Health Values. Selivanova APharmacoeconomics2018within study comparison
Comparing the UK EQ-5D-3L and English EQ-5D-5L Value Sets.Mulhern BPharmacoeconomics2018between study comparison
Parallel Valuation: A Direct Comparison of EQ-5D-3L and EQ-5D-5L Societal Value SetsLaw EMedical Decision Making2018within study comparison
Quantification of the level descriptors for the standard EQ-5D three-level system and a five-level version according to two methods. Janssen MFQuality of Life Research2008within study comparison
Overview, Update, and Lessons Learned From the International EQ-5D-5L Valuation Work: Version 2 of the EQ-5D-5L Valuation Protocol.Stolk EValue Health2019methodological advances
Quality Control Process for EQ-5D-5L Valuation Studies.Ramos-Goñi JMValue Health2017methodological advances
EuroQol Protocols for Time Trade-Off Valuation of Health Outcomes.Oppe MPharmacoeconomics2016methodological advances
Handling Data Quality Issues to Estimate the Spanish EQ-5D-5L Value Set Using a Hybrid Interval Regression Approach.Ramos-Goñi JMValue Health2018methodological advances

(Version 16OCT2018)

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