Implications for CEA
There is hardly any evidence on the implications for cost-effectiveness ratios when switching from EQ-5D-3L to EQ-5D-5L. Some work has been done for England, but researchers had no paired 3L and 5L data, a gap they filled with mapping. These indirect methods attribute to uncertainties, in particular in view of concerns about the validity of estimates of QALY gains when based on mapping algorithms. It is difficult to disentangle difference that relate to the mapping and ‘real’ difference between 3L and 5L responses.
|Study Title||First Author||Journal||Year||Type|
|EQ-5D-5L versus EQ-5D-3L: The Impact on Cost Effectiveness in the United Kingdom||Hernandez Alava M||Value in Health||2018||Comparison based on mapping|
|A (five-)level playing field for mental health conditions?: exploratory analysis of EQ-5D-5L-derived utility values||Camacho EM||Quality of Life Research||2018||Simulation|
|Econometric modelling of multiple self-reports of health states: The switch from EQ-5D-3L to EQ-5D-5L in evaluating drug therapies for rheumatoid arthritis||Hernandez Alava M||J Health Economics||2017||Comparison based on mapping|
|The Impact of Moving from EQ-5D-3L to -5L in NICE Technology Appraisals||Pennington B||Pharmacoeconomics||2018||comparison based on mapping|
|Cost-Utility Analysis Using EQ-5D-5L Data: Does How the Utilities Are Derived Matter?||Yang F||Value Health||2019||comparison based on mapping|